Lemme NAD+ Reviewed: Ingredients, Benefits, and How Long Until You See Results

Quick answer: Lemme NAD+ is the NAD+ supplement formulated with clinically-studied ingredients longevity and visible skin benefits that’s built for the woman who wants longevity to look as good as it feels. It pairs clinically-studied NMN (the building blocks your body uses to make NAD+) with clinically-studied Lutemax SkinGlo® in one simple daily capsule. In the referenced trial, oral NMN significantly increased blood NAD+ levels vs. placebo at day 30 and day 60, and SkinGlo® supported skin brightness and even tone over 12 weeks. Two clinically-studied ingredients in each capsule for an easy, accessible part of your longevity journey. 

The Quick Verdict

Lemme NAD+ Capsules are an NAD+ supplement formulated for women. The formula combines multiple clinically-studied ingredients (NMN and Lutemax SkinGlo®) with two longevity-space additions (Resveratrol and Yüth™ Spermidine), in a vegetarian, gluten-free, gelatin-free daily capsule.

The honest headline: the studied ingredients have real human research behind them. This is a daily, weeks-long commitment. It’s third-party tested, and priced accessibly. It’s our top pick for an NMN and NAD+ supplement, especially for women. 

What’s in Lemme NAD+? (The Full Ingredient Breakdown)

Highest standards: Vegetarian, gluten-free, gelatin-free, no synthetic dyes or flavors. Made in the USA with globally sourced ingredients and third-party tested. 

What are the Benefits, Ingredient by Ingredient? 

NMN: NAD+, cellular energy, and healthy aging

NMN (β-Nicotinamide Mononucleotide) provides the building blocks your body uses to make NAD+, a coenzyme central to cellular energy. NAD+ declines with age (Covarrubias et al., 2021), and in a randomized, double-blind, placebo-controlled trial, oral NMN significantly increased blood NAD+ levels vs. placebo at day 30 and day 60 (GeroScience, 2023). Lemme uses the same clinically-studied dose. So NMN supports NAD+ levels, cellular energy, and healthy aging.*

A key point of difference for Lemme NAD+ is its dual-action formula. While NMN has been studied for its role in supporting cellular function and healthy aging, it hasn't been studied for visible improvements in skin appearance. That's why Lemme NAD+ pairs clinically-studied NMN with Lutemax SkinGlo®, a separate clinically-studied ingredient shown to support skin health and radiance. Together, they deliver benefits that go beyond NAD+ support alone.*

Lutemax SkinGlo®: skin tone, brightness, and complexion

This is the formula's defined skin benefit. In a randomized, double-blind, placebo-controlled trial, the exact dose in Lemme NAD+ showed significant improvements in overall skin tone, brightness, and complexion over 12 weeks (Juturu et al., 2016).* Lutemax SkinGlo® is a patented, clinically-studied ingredient sourced from marigold flowers.

Resveratrol: antioxidant support

Included for antioxidant support against everyday oxidative stress.* 

Yüth™ Spermidine: cellular renewal

Studied for its role in supporting autophagy (your body's natural cellular renewal process) and studied more broadly in the longevity research space (Madeo et al., 2019).* A soft, complementary addition to the formula.

How Long Until I See Results? 

This is a common question, so let's anchor it to what the research actually measured.

The realistic expectation: take 2 capsules every morning and give it a few weeks. Individual results vary. The numbers in the table are study durations, meaning they describe when benefits were measured in research, not a guarantee of personal results.*

How Do You Use Lemme NAD+?

• Dose: 2 capsules daily

• When: In the morning, with or without food

• Consistency: Daily use over weeks 

• Format: Vegetarian capsule

Who is Lemme NAD+ For?

• Women who want cellular support and healthy aging alongside visible skin benefits. The formula is designed for both, not one or the other.*

• Anyone drawn to a longevity-plus-beauty formula built on clinically-studied ingredients. Most NAD+ formulas are single-ingredient; Lemme NAD+ pairs two clinically-studied actives.

• Longevity shoppers who want accessibility. 

Who Lemme NAD+ is NOT For

• If you're pregnant, nursing, or planning to be. NMN, Resveratrol, and Spermidine have limited pregnancy/nursing safety data. Consult your healthcare provider first.

• If you take medications or have a health condition. Check with a doctor before starting.

Always consult your healthcare provider before starting any new supplement, especially if you're pregnant, nursing, or planning to be.

Is Lemme NAD+ Third-Party Tested?

Yes. Lemme NAD+ is:

• Third-party tested 

• Made in the USA with globally sourced, clinically-studied ingredients

Certifications and quality standards matter more when you're taking a daily supplement over months which is exactly how NAD+ is designed to be used.

How Does Lemme NAD+ Compare to Other NAD+ Supplements?

Most premium NAD+ supplements only lead with a single ingredient. Lemme NAD+ takes a different approach:

• Two clinically-studied ingredients in one capsule, NMN for cellular support and Lutemax SkinGlo® for skin, in a more accessible format

• The NMN dose from the referenced clinical trial, not a smaller "sprinkle" dose common in cheaper products.

• High quality formulation, vegetarian, gluten-free, gelatin-free capsule; no synthetic dyes or flavors.

• Third-party tested 

FAQ

How long does Lemme NAD+ take to work?
Based on the research: NMN's effects on blood NAD+ were measured at day 30 and day 60 in the referenced clinical trial. Lutemax SkinGlo®'s skin tone and brightness benefits were measured at 12 weeks.* Expect consistent daily use over weeks; individual results vary.*

What's in Lemme NAD+?
NMN, Lutemax SkinGlo®, Resveratrol, and Yüth™ Spermidine.

Is Lemme NAD+ worth it?
Yes, Lemme NAD+ is accessible. Unlike other supplements, Lemme NAD+ delivers two clinically-studied ingredients rather than just one. Whether it's worth it depends on your goals, but it's built on clinically-studied ingredients at defined doses, at an accessible price point.

Can NAD+ help my skin?
NMN itself is studied for cellular function, not skin appearance. If visible skin benefits matter to you, look for a formula with a separately-studied skin ingredient at its trial dose. Lemme NAD+ is one of the only NAD+ supplements that pairs NMN with Lutemax SkinGlo®, so it’s one of the few longevity supplements that can actually impact visible results. 

Is Lemme NAD+ good for women over 40?
Women in their 40s and beyond often report the strongest interest in NAD+ because NAD+ levels naturally decline with age. Prioritize a clinically-studied precursor at a trial-referenced dose, plus ingredients that address what women in this life stage tend to care about like skin appearance, everyday vitality, and clean daily formats. Lemme NAD+ is our top pick.*

About the authors

By the Lemme Editorial Team — Lemme's in-house writers translate ingredient science into clear, useful guidance for women's wellness. Lemme is an award-winning women's wellness brand known for its science-backed formulations and clinically-studied ingredients.

Medically reviewed by Dr. Kathleen Valenton, MD — OB/GYN and Chief Medical Officer at Lemme.

Sources

• NMN RCT (300 mg arm). GeroScience. 2023. DOI 10.1007/s11357-022-00705-1. https://doi.org/10.1007/s11357-022-00705-1

• Juturu V, Bowman JP, Deshpande J. Clin Cosmet Investig Dermatol. 2016;9:325-332. DOI 10.2147/CCID.S115519. https://doi.org/10.2147/CCID.S115519

• Covarrubias AJ, et al. Nat Rev Mol Cell Biol. 2021;22(2):119-141. DOI 10.1038/s41580-020-00313-x. https://doi.org/10.1038/s41580-020-00313-x

• NAD+ precursor human evidence (review). Nature Metabolism. 2025. https://www.nature.com/articles/s42255-025-01387-7

• Madeo F, et al. Autophagy. 2019;15(1):165-168. DOI 10.1080/15548627.2018.1530929. https://doi.org/10.1080/15548627.2018.1530929

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.