Lemme Burn vs. Arrae MB-1 vs. Burn XT: Which Metabolism Supplement Makes the Most Sense?

Reviewed by Dr. Kathleen Valenton, MD, Double Board-Certified OB/GYN

5 min read  |  9 citations  |  March 23, 2026

If you’re comparing Lemme Burn vs. Arrae MB-1 vs. Burn XT, the biggest differences come down to stimulant load, label transparency, mechanism of action, and price.

Three metabolism supplements. Three very different formulas. They all claim to support fat burning, but the ingredients, mechanisms, and use cases are miles apart. This guide breaks down Lemme Burn, Arrae MB-1, and Burn XT on what actually matters: formulation quality, ingredient science, caffeine content, label transparency, and price.

Quick Summary: Which One Wins?

The short answer: it depends on what you're actually looking for.

•   Lemme Burn Capsules:  Lemme Burn Capsules (~$34/month subscribe, $40 one-time) is built around Actiponin®, a patented AMPK-activating ingredient with a 12-week human clinical trial behind it, paired with a high-dose Green Tea Extract standardized to 50% EGCG. No added caffeine. Fully transparent label. No proprietary blend. Currently ranked #1 Best Seller in Fat Burners on Amazon.9 Lemme Burn is also Clean Label Project Certified.

•   Arrae MB-1:  Arrae MB-1 (~$65/month) takes a multi-pathway approach, combining AMPK activation, botanical support, and gut health via probiotics. The catch: it uses a proprietary blend, so you can't see individual ingredient doses on the label.

•   Burn XT by Jacked Factory:  Burn XT by Jacked Factory (~$25-35/month) is a high-stimulant thermogenic with 270 mg of caffeine per serving. It's made for hard training sessions, not daily metabolic support.

For most people looking for a daily, non-stimulant metabolism supplement, Lemme Burn is the most balanced option; Burn XT is more of a workout thermogenic, while Arrae MB-1 is a broader but less transparent premium formula.

Before You Compare Bottles, Understand the Biology

Walk through any supplement store and you'll find dozens of products promising to "boost your metabolism" and "support fat burning." Those phrases can mean very different things depending on how a formula actually works.

There are three main approaches these products take:

•   AMPK activation: AMP-activated protein kinase is an enzyme the body uses to regulate how cells produce and store energy. When AMPK is activated, it promotes fat oxidation and inhibits fat synthesis, essentially mimicking some metabolic effects of exercise at the cellular level.

•   Thermogenesis and CNS stimulation: Thermogenesis and CNS stimulation: Caffeine and capsaicin-derived compounds raise body temperature and stimulate the central nervous system, producing short-term increases in calorie burn and energy.

•   Multi-pathway support: Multi-pathway support: Some formulas combine AMPK activation, botanical support, and probiotic gut health to hit metabolism from several angles at once.

Knowing which mechanism a product uses helps you decide whether it fits your goals, lifestyle, and caffeine tolerance before you spend the money.

 
At a Glance: Lemme Burn vs. Arrae MB-1 vs. Burn XT

Lemme Burn Capsules: Patented AMPK Science, No Added Caffeine

Lemme Burn takes a deliberately focused approach: two capsules, no proprietary blend, and a formula centered on one patented, clinically studied ingredient: Actiponin®.

What's in It

•   Actiponin® (Gynostemma pentaphyllum, leaf extract)

•   Green Tea Extract (standardized to 98% polyphenols, 50% EGCG)

•   Vitamin B6 (as Pyridoxal 5-Phosphate, the active form)

•   Vitamin B12 (as Methylcobalamin, the active form)

The Science Behind Actiponin®

Actiponin® is not a standard Gynostemma pentaphyllum extract. It's produced through a specific heat-processing method that concentrates two active compounds, damulin A and damulin B, to levels roughly 10x higher than conventional extracts.

These damulins activate AMPK, the enzyme that functions as the cell's energy sensor. Preclinical research suggests damulins A and B activate AMPK, which is associated with increased fatty acid oxidation and glucose uptake.

The human evidence is what separates Actiponin® from most other ingredients in this category. A 12-week, randomized, double-blind, placebo-controlled trial of 80 adults with obesity found that the Actiponin® group (450 mg/day) showed statistically significant reductions in:

•   Total abdominal fat area (P = 0.044)

•   Body fat mass (P < 0.0001)

•   Percent body fat (P < 0.0001)

•   BMI (P < 0.05)

 No significant changes in food intake were observed, and no clinically significant adverse effects were reported. The fat loss effects were independent of appetite suppression or stimulant effects.

A separate 16-week RCT of ActivAMP® (from the same Gynostemma family) in 117 overweight adults found significant reductions in fat mass and BMI versus placebo, with gender-specific patterns in where fat was lost.

Green Tea Extract, B6 & B12

The Green Tea Extract in Lemme Burn is standardized to 50% EGCG. Meta-analyses of EGCG supplementation show moderate increases in energy expenditure and a shift in the body's fuel preference toward fat.

Both B vitamins are included in their most bioavailable forms: Pyridoxal 5-Phosphate (B6) and Methylcobalamin (B12). These play essential roles in energy metabolism and macronutrient processing at the cellular level.

What Makes Lemme Burn Different

There's no proprietary blend hiding doses and no added caffeine. The only caffeine present is the naturally occurring trace amount in the green tea extract, which is minimal compared to a standard cup of coffee. That means the product can be taken morning or evening without the jitter or sleep concerns that come with stimulant-heavy supplements, though anyone with sensitivity to any caffeine should keep that in mind.

The formula is vegetarian, gluten-free, non-GMO, and responsibly formulated with no synthetic colors or flavors, no magnesium stearate, and no silicon dioxide. Lemme Burn is Clean Label Project Certified, a third-party standard that tests for over 400 contaminants including heavy metals and pesticides. Lemme's SuppCo Elite score places it significantly higher than most competing supplement brands on the market.

Price: $34/month subscribe  |  $40 one-time (60 capsules, 30 servings)

Arrae MB-1: Broad-Spectrum Formula, Opaque Dosing

Arrae MB-1 targets the metabolism problem from multiple directions: AMPK activation, botanical metabolic support, and gut health via probiotics. That's an interesting approach. The formulation decision to use a proprietary blend, though, makes it hard to assess.

What's in It

MB-1 contains a proprietary blend (895 mg total) of seven ingredients: Green Tea Extract, African Mango Seed Extract (IGOB131®), Cissus Leaf Extract (CQR-300®), Grains of Paradise Seed Extract, Bifidobacterium lactis B420 (10 billion CFU), Vitamin B6 (as Pyridoxal 5-Phosphate, 5 mg), and Chromium Picolinate (500 mcg). Individual doses for most ingredients are not on the label.

The Science and the Formulation Consideration

Arrae references 15 clinical trials across its 7 ingredients. Some of those have genuine supporting data, IGOB131® and B. lactis B420 have been studied independently. But there's no clinical trial on MB-1 as a complete formula, and without disclosed individual amounts, it's not possible to verify whether each ingredient is present at the dose used in the clinical research cited. In supplement science, dose matters considerably.

MB-1 also contains caffeine from green tea extract, though the exact amount isn't disclosed. Worth noting if you're caffeine-sensitive, taking the product in the afternoon, or already consuming caffeine from other sources.

Price: ~$65/month (60 capsules, 30 servings)

Burn XT by Jacked Factory: High-Stim Thermogenic for Hard Training Days

Burn XT is a different product category. It's not a daily metabolic support supplement. It's a stimulant-based thermogenic designed to amplify training sessions through energy, focus, and heat generation.

What's in It

•   Acetyl L-Carnitine HCl: 700 mg

•   Green Tea Leaf Extract (98% polyphenols, 45% EGCG): 450 mg

•   Caffeine Anhydrous: 270 mg per 2-capsule serving

•   Capsimax® Cayenne Pepper Extract: 50 mg

•   BioPerine® (black pepper): 5 mg

The Science and the Caffeine Consideration

Burn XT is transparent about its label, no proprietary blend. The 450 mg of green tea extract per serving is a meaningful dose, and Capsimax® has its own clinical data for thermogenic support. Burn XT has also been included in a published clinical study on its formula.

The 270 mg of caffeine per 2-capsule serving is the dominant variable here. That's roughly equivalent to two and a half to three cups of coffee in two capsules. At the maximum dose of 4 capsules per day, total caffeine intake would approach or exceed the 400 mg daily upper limit noted in established dietary guidance. Individuals who are pregnant, nursing, caffeine-sensitive, or managing a health condition should consult their healthcare provider before using any high-stimulant supplement.

That caffeine dose will produce a real short-term energy and metabolic effect, but it also means this product can't be taken in the afternoon without risking sleep disruption. It shouldn't be stacked with other caffeinated products.

For users who specifically want a high-stim thermogenic before training, that stimulant-heavy profile may be a feature rather than a drawback.

Price: ~$25-35/month (60 capsules at standard 2-capsule/day dosing)

Who Is Each Product For?

Choose Lemme Burn if you want a transparently formulated daily supplement you can take with or without food, morning or evening; if you prefer a formula with an ingredient-level clinical trial behind its star ingredient; or if you're looking for a sustainable metabolism support routine rather than a pre-workout energy boost.

Choose Arrae MB-1 if you want a supplement targeting multiple metabolic pathways including gut health; don't mind moderate caffeine in your formula; and are comfortable with a proprietary blend at a premium price point.

Choose Burn XT if you train hard (especially morning sessions) and want acute energy, focus, and thermogenic effects to fuel your workouts; have a high caffeine tolerance; and are focused on short-term performance rather than daily metabolic wellness.

Who Should Not Use These?

If you are pregnant, breastfeeding, highly caffeine-sensitive, taking medications, or dealing with a medical condition affecting weight or metabolism, consult a healthcare provider before using any metabolism supplement. High-stimulant products deserve extra caution.

Our Verdict

For a metabolism supplement you can take every day without synthetic caffeine, hidden doses, or a $65/month price tag, Lemme Burn is the most compelling option in this comparison.

Its star ingredient, Actiponin®, is backed by a peer-reviewed 12-week clinical trial showing significant reductions in body fat mass, percent body fat, and BMI in humans,1 with a well-characterized mechanism at the cellular level. Paired with a high-dose EGCG-standardized green tea extract, and bioavailable B vitamins, the formula delivers a science-supported daily routine at $34/month (subscribe) or $40 one-time. No added caffeine. No hidden doses. Clean Label Project Certified. And ranked #1 in Fat Burners on Amazon.

Burn XT delivers on its thermogenic promise for the right person, but it's a workout supplement first. And Arrae MB-1's multi-mechanism approach is interesting, but at $65/month with a proprietary blend, it's hard to evaluate whether each ingredient is actually present at the dose that matches the research cited.

Frequently Asked Questions

Does Lemme Burn contain caffeine?

Lemme Burn contains no added caffeine. The formula includes a Green Tea Extract standardized to 98% polyphenols and 50% EGCG, which naturally contains a trace amount of caffeine, far less than a cup of coffee. This makes it suitable for morning or evening use and appropriate for people managing their overall caffeine intake. Those particularly sensitive to any caffeine should be aware of this.

How long does Lemme Burn take to work?

The Actiponin® clinical trial ran for 12 weeks, and statistically significant reductions in body fat mass, percent body fat, and BMI were observed over that period. Like most metabolism support supplements, Lemme Burn is built for consistent daily use rather than single-dose effects. Most users who respond to the formula report noticing changes over weeks, particularly when combined with regular exercise and a balanced diet.

What is AMPK and why does it matter for metabolism?

AMPK (AMP-activated protein kinase) is the body's cellular energy sensor. When activated, it promotes fat oxidation and inhibits fat synthesis, effects that resemble some of the metabolic benefits of exercise at the cellular level. Actiponin®, the patented core ingredient in Lemme Burn, has been shown in peer-reviewed research to activate AMPK in metabolic tissues, which is the mechanism behind its effects on body fat and BMI in clinical trials.

Is Lemme Burn safe for women?

Lemme Burn's formula has a strong safety profile based on available research on its individual ingredients. The 12-week Actiponin® RCT reported no clinically significant adverse effects. As with any supplement, women who are pregnant, breastfeeding, or managing a health condition should consult their healthcare provider before use.

What makes Lemme Burn different from other fat burner supplements?

Most fat burners rely primarily on high-dose caffeine and stimulants for their effects. Lemme Burn works differently: its core mechanism is AMPK activation via Actiponin®, a patented ingredient with a published 12-week human trial showing significant reductions in body fat mass and BMI, independent of appetite suppression or stimulant effects. The formula is fully transparent with no proprietary blend, contains no added caffeine, and is vegetarian, gluten-free, non-GMO, and Clean Label Project Certified. It currently ranks #1 Best Seller in Fat Burners on Amazon (as of March 21, 2026).

This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any new supplement regimen.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

 References

1. Park SH, et al. Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial. Obesity. 2014;22(1):63-71. https://pubmed.ncbi.nlm.nih.gov/23804546/

2. Gauhar R, et al. Heat-processed Gynostemma pentaphyllum extract improves obesity in ob/ob mice by activating AMP-activated protein kinase. Biotechnol Lett. 2012;34(9):1607-1616. https://link.springer.com/article/10.1007/s10529-012-0944-1

3. Nguyen PH, et al. New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum. Bioorg Med Chem. 2011;19(21):6254-6260. https://pubmed.ncbi.nlm.nih.gov/22000935/

4. Rao A, et al. The effect of an orally-dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight adults: a double-blind, randomised, placebo-controlled study. J Hum Nutr Diet. 2022;35(2):333-348. https://pubmed.ncbi.nlm.nih.gov/34323337/

5. Kapoor MP, et al. Physiological effects of epigallocatechin-3-gallate (EGCG) on energy expenditure for prospective fat oxidation in humans: a systematic review and meta-analysis. J Nutr Biochem. 2017;43:1-10. https://pubmed.ncbi.nlm.nih.gov/27883924/

6. Rondanelli M, et al. Effect of acute and chronic dietary supplementation with green tea catechins on resting metabolic rate, energy expenditure and respiratory quotient: a systematic review. Nutrients. 2021;13(3):644. https://pmc.ncbi.nlm.nih.gov/articles/PMC7922336/

7. NIH Office of Dietary Supplements. Vitamin B6: Fact Sheet for Health Professionals. Updated December 2023. https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

8. NIH Office of Dietary Supplements. Vitamin B12: Fact Sheet for Health Professionals. Updated June 2024. https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

9. Amazon Best Seller Rank: #1 in Fat Burners. Lemme Burn Capsules. Verified March 15, 2026. https://www.amazon.com/Lemme-Clinically-Metabolic-Activator-Actiponin/dp/B0CTBJX4G5

About the Expert Reviewer

Kathleen Valenton, MD is a double board-certified OB/GYN at Rodeo Drive Women's Health Center in Beverly Hills, CA, with over a decade of experience in women's health. She completed her internship and residency at Cedars-Sinai Medical Center, where she remains an attending physician, after earning her Medical Degree from the University of Vermont College of Medicine and dual Bachelor's and Master's degrees in Psychology from UC Berkeley. Dr. Valenton is also the Chief Medical Officer at Lemme. Her clinical research interests span mental health, hormonal health, infertility, PCOS, and menopause. Dr. Valenton is known for her expertise in pelvic pain, infertility evaluations, and minimally invasive surgery, and remains actively involved in resident education and physician-nursing collaboratives at Cedars-Sinai.